Multi-criteria decision analysis (MCDA): testing a proposed MCDA framework for orphan drugs

Multi-criteria decision analysis (MCDA): testing a proposed MCDA framework for orphan drugs

BACKGROUND Since the introduction of the orphan drugs legislation in Europe, it has been suggested that the general method of assessing drugs for reimbursement is not necessarily suitable for orphan drugs. The National Institute for Health and Clinical Excellence indicated that several criteria other than cost and efficacy could be considered in reimbursement decisions for orphan drugs. This st...

Using Multiple Criteria Decision Analysis (MCDA) to make coverage decisions: a methodological framework

Results We propose a methodological process comprising five distinct phases (problem structuring, model building, model assessment, model appraisal and development of action plans), outline the stages involved in each phase and discuss their relevance in the HTA process. Additionally, criteria and attributes need to satisfy a set of desired properties, otherwise the process of preference elicit...

Optimal Selection of Clustering Algorithm via Multi-Criteria Decision Analysis (MCDA) for Load Profiling Applications

Due to high implementation rates of smart meter systems, considerable amount of research is placed in machine learning tools for data handling and information retrieval. A key tool in load data processing is clustering. In recent years, a number of researches have proposed different clustering algorithms in the load profiling field. The present paper provides a methodology for addressing the af...

Aggregation of Priorities in Multi-Criteria Decision Analysis (MCDA): Connecting Decision Spaces in the Cognitive Space

In Multi-Criteria Decision Analysis, the well-known weighted sum method for aggregating normalised relative priorities ignores the unit of scale that may vary across the criteria and thus causes rank reversals. A new aggregation rule that explicitly includes the norms of priority vectors is derived and shown as a remedy for it. An algorithmic procedure is presented to demonstrate how it can as ...

Building Criteria: a Prerequisite for Mcda